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Home » Animal Research Models
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SAGE™ Labs partners with the leading minds in ADMET, neurobiology, cardiovascular biology, and oncology to develop rodent research models for advanced disease research. We will continue to expand our portfolio of proprietary, off-the-shelf knockout rats to provide the scientific community access to popular models with unprecedented speed and efficiency.

Knockout Models

Neuroscience

Rats

  • Parkinson's
    Disease
  • Lrrk1
  • Lrrk2
  • Park2 (Parkin)
  • Park6 (Pink1)
  • Park7 (DJ-1)

 

  • Autism
  • Fmr1
  • Nlgn3
  • Pten
  • MeCP2
  • Nrxn1
  • Cacna1c
  • Grm5

 

  • Schizophrenia
  • Disc1
  • Bdnf

 

  • Alzheimer's
    Disease
  • ApoE
  • Bdnf

Admet

Rats

  • Mdr1a
  • Mrp1
  • Mrp2
  • p53
  • Bcrp

Cardiovascular

Rats

  • ApoE
  • Leptin
  • Ldlr

Rabbits

  • Model 1
  • Model 2

Oncology

Rats

  • Foxn1
  • p53
  • Rag1
  • Rag2
  • DNAPk

Outbred / Inbred Models

Outbred Models

Rats

  • Sprague Dawley
  • Cotton Rats

Mice

  • ICR
  • NIH Athymic Nude
  • Swiss Webster
  

Inbred Models

Mice

  • C57BL/6
  • Balb/c

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SAGE Labs News ::
Sigma® Life Science Announces Gene Knockout Rat Models for Cardiovascular, Diabetes and Atherosclerosis Research
Dec 7 2011
Autism Speaks to present data on the behavior of the first knockout rat models of Autism
Nov 9 2011
Sigma Transgenic Rats | Knockout Rat Models
Nov 4 2010
Preclinical Model | Knockout Animals | Knock Out Animals
Oct 27 2010
Knockout Animals | Knock Out Animals
Sep 15 2010
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SAGEspeed

SAGEspeed™ provides custom knockout rats and mice in as few as 5 months. Learn More

SAGEsearch Gene Information Database

SAGEsearch is a gene-oriented information database. Enter a gene symbol, name, or accession ID to access literature, expression, regulation, SNP, and disease-related data.

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Search by Model Type and/or Keyword

Use the dropdown list below to select an application. Additionally you can search with Keyword in the selected Application. If you are not sure about which Application your model may exist in, make sure to keep the Application dropdown set to All and search by Keyword.
Search Results >
  • Cotton Rats

    The cotton rat is an excellent research model for vaccine development. It is highly susceptible to human infectious agents, including: Respiratory Syncytial Virus, Herpes Simplex, Parainfluenze, Monkey Pox, and emerging viruses.

  • Sprague Dawley

    The outbred multipurpose model of choice is the Sprague Dawley Rat. A general model for the study of human health and disease, this outbred rat serves as an excellent model for toxicology, reproduction, pharmacology, and behavioral research areas.

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