1. Metabolic Similarity
The metabolic physiology of the rat is closer to humans than in mice. This makes the rat a better species to study metabolic disorders and the pharmacokinetic/pharmacodynamic characteristics of drugs.
2. Superior Behavior Modeling
The rat is the preferred species for modeling cognition, psychotherapeutic, affective, and neurological disorders.
3. Physiological Similarity
Rat physiology is better suited for the study of human toxicology, cardiovascular disease, and immunology.
4. Technical Advantages
Larger size of rats allows sophisticated surgical manipulations. The ability to harvest a larger volume of blood/CSF and tissue enables optimal experimental readouts.
Research Models
SAGE® Labs partners with the leading minds in ADMET, neurobiology, cardiovascular biology, and oncology to develop rodent research models for advanced disease research. We will continue to expand our portfolio of proprietary, off-the-shelf knockout rats to provide the scientific community access to popular models with unprecedented speed and efficiency.
Knockout Models |
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Outbred / Inbred Models |
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