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Knockout Rats Listed by Research Area
Outbred Mice Outbred Rats Inbred Mice

Benefits of Rats

Metabolic Similarity The metabolic physiology of the rat is closer to humans than in mice. This makes the rat a better species to study metabolic disorders and the pharmacokinetic/pharmacodynamic characteristics of drugs.
Superior Behavior Modeling The rat is the preferred species for modeling cognition, psychotherapeutic, affective, and neurological disorders.
Physiological Similarity Rat physiology is better suited for the study of human toxicology, cardiovascular disease, and immunology.
Technical Advantages Larger size of rats allows sophisticated surgical manipulations. The ability to harvest a larger volume of blood/CSF and tissue enables optimal experimental readouts.