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SAGE Labs Models in Development ::
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  • Ank3 Bi-Polar disorder Neuroscience

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  • CACNA1C Bi-Polar disorder - Neuroscience

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  • Oprd1 (DOR1) - pain/drug addiction - Neuroscience

    Opioid receptor deficient rats could be an advantage to nociception research due to their higher cognitive abilities over mice.

  • Oprk1 (KOR1) - pain/drug addiction - Neuroscience

    Opioid receptor deficient rats could be an advantage to nociception research due to their higher cognitive abilities over mice.

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Animal Research Models Banner
Prkdc Knockout Rat
Model Detail >
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Prkdc Knockout Rat
Nomenclature: SD- Prkdc tm1sage
Genotype: Homozygous
Product number: In Development
List pricing: TBD

Request a quote and a SAGE™ Labs research specialist will contact you with an estimated price and delivery date.

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Description - This model will contain a bi-allelic deletion within the Prkdc (protein kinase, DNA-activated, catalytic polypeptide) gene, which is a component of the autoimmune antigen Ku.
Additional Information
Loss of Prkdc function results in severe combined immunodeficiency due to lack of V(D)J recombination.
Research Applications

Autoimmune disorders
Xenograft studies

 
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