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SAGE Labs Models in Development ::
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  • Oprm1 (MOR1) - pain/drug addiction - Neuroscience

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  • Ank3 Bi-Polar disorder Neuroscience

    Ank3 was identified through genome association studies to be a candidate for Bi-Polar Disorder.

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Animal Research Models Banner
Foxn1 Knockout Rat
Model Detail >
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Foxn1 Knockout Rat
Nomenclature: SD- Foxn1 tm1sage
Genotype: Homozygous
Product number: In Development
List pricing: TBD

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Description - This model will contain a bi-allelic deletion within the Foxn1 gene, encoding for the Forkhead box protein n1, which is a transcription factor involved in generation of T lymphocytes.
Additional Information
T cells are critical components for an adaptive immune system. Rats deficient in Foxn1 protein produce no mature T cells and are also athymic nude, making them useful for xenografts and allografts.
Research Applications

Autoimmune disorders
Xenograft studies

 
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