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From SAGE™ Labs - Archive

April 2010

Sigma® Life Science extends research model portfolio into Oncology and Carcinogenicity screening

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St. Louis, MO. – April 19, 2010 – Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich® (NASDAQ: SIAL), today introduced the world’s first p53 ‘knockout’ rat model, an important development that is expected to, due to the rat’s closer physiological and metabolic similarity to humans, significantly improve timelines for carcinogenicity screening and reduce time to market for therapeutics.

March 2010

Sigma-Aldrich Further Expands In Vivo Biology Offering with Acquisition of Ace Animals, Inc.

FORWARD INQUIRIES TO:
Sigma-Aldrich

Sarah Bruno
+ 314-286-7810
sarah.bruno@sial.com

MEDIA INQUIRIES: Impress Public Relations
Richard Kerns
+ 44 (0)161-728-5880
richard@impress-pr.com

Mark Button
+ (1) 503-616-3817
mark@impress-pr.com

SIGMA-ALDRICH FURTHER EXPANDS IN VIVO BIOLOGY OFFERING
WITH ACQUISITION OF ACE ANIMALS, INC

Acquistion Enhances SAGE Labs’ Rodent Husbandry Capabilities; Adds New Models to Product Portfolio and Strategic Location for Animal Distribution

Sigma Life Science Introduces World's First Suite of Knockout Rats for ADME/Tox Applications

ST. LOUIS, March 8 /PRNewswire-FirstCall/ -- Sigma® Life Science, an innovative brand of Sigma-Aldrich® (Nasdaq: SIAL), today extended its portfolio of knockout rat models with the announcement of a new suite of models designed to facilitate more predictive absorption, distribution, metabolism, excretion and toxicity (ADME/Tox) studies.

January 2010

Generation of Knockout Rats with X-Linked Severe Combined Immunodeficiency (X-SCID) using Zinc-Finger Nucleases

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December 2009

Sigma-Aldrich's Targeted Knockout Rat Ranks in Top 5 of The Scientist Magazine's Top 10 Innovations for 2009

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Sigma-Aldrich's Targeted Knockout Rat Ranks in Top Five of The Scientist Magazine's Top 10 Innovations of 2009
World's First Knockout Rat Developed Using Proprietary CompoZr ZFN(TM) Technology; 2009 Award Builds on 2008 CompoZr ZFN Win; Encompasses Proof of Concept