SAGE Labs utilizes state-of-the-art barrier facilities for housing of all laboratory mice and rats. Technicians follow carefully written and approved Standard Operating Procedures when working in, and moving about, the barrier facility. Moving between rooms in the facility is carefully controlled with numerous restrictions in place. Supplies can only enter the barrier facility after decontamination and through a dedicated entry portal. Each barrier facility room is treated as a self-contained unit, with its own airflow system and dedicated equipment. In addition, individually ventilated rack systems are utilized to host the Immune-comprised and controlled lines inside the production rooms.
SAGE Labs – Boyertown, formerly known as Ace Animals, was acquired in March 2010. The Boyertown site has been AAALAC accredited since 2001 and continues to maintain full accreditation status since acquisition. The most recent triennial visit in February 2011, supports and applauds the high standard of husbandry, production, and operations by reporting no suggestions for improvement in any areas.
Data reproducibility and consistency require use of laboratory mice and rats in research that are free from pathogenic organisms. SAGE Labs is committed to an extensive health monitoring system as part of our comprehensive quality control program. We are fully dedicated to providing both health monitoring data as well as a complete description of our health monitoring program in order to give you confidence in the quality of our research models. Contact us at email@example.com for more details.
SAGE Labs utilizes a quarterly sentinel program to survey the health status of our animal colonies to identify unexpected infection. The sentinels are exposed to colony animals’ dirty bedding for eight to twelve weeks, enough time for animals to develop antibodies.
Genetic monitoring is critical to maintain the specific characteristics of any strain. SAGE Labs provides our customers the confidence in knowing genetic integrity is a high priority within our business. SAGE Labs relies on the extensive training of our animal technicians, documented observations of specific strain characteristics, and the use of molecular genotyping to ensure the quality of our genetically modified strains. Our quality control and checkpoint processes ensure our customers can rely on the reproducibility of experimental data between groups and over time.
AALAS training programs are utilized to provide our staff with ongoing professional development in animal health, husbandry and genetics. Technicians remain in compliance with OLAW policies and are encouraged to seek professional certifications. Our experienced staff trains and mentors the remaining staff, which must adhere to Standard Operating Procedures for all handling of animals. In addition to professional veterinary staff, an IACUC committee maintains adherence to sound animal ethics and welfare policy for each SAGE Labs facility.